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II FLORENCE INT. SYMPOSIUM ON ADVANCES IN CARDIOMYOPATHIES

Palazzo Congressi (FI)
26/09/2012 - 28/09/2012

	Programma Evento
	Foto: 29
	Video: 5
	Info

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26/09/2012

PLENARY-ROOM

17:00 - 17:20
OFFICIAL OPENING: WELCOME BY AUTHORITIES, DIRECTORS AND WG CHAIRMAN

Inaugurazione

17:20 - 19:40
SESSION 1 - EMERGING CONCEPTS IN CARDIOMYOPATHIES

Elliott P.
Classification of cardiomyopathies: news for the future

Ho C.
Molecular basis of cardiomyopathies: new genes and technologies

Olivotto I.
Pharmacological treatment : high time for evidence

Bonow R.
USA, Europe and the rest of the word: differences and similarities

Thiene G.
Lessons from history: "GALILEO as a patient"

ROOM-1

09:00 - 13:00
MINICOURSE - BASIC SCIENCE - THE CARDIOMYOCYTE AND ITS ENVIRONMENT: FROM PATHOPHYSIOLOGY TO NOVEL THERAPEUTIC TARGETS

Poggesi C.
Anatomy and electromechanical properties

Tardiff J.
Electrical and mechanical dysfunction

A. Donati, E. Pasquini
Inborn error of metabolism

Redwood C.
Signalling pathways for left ventricular hypertrophy

Cerbai E.
Molecular targets for disease-specific treatment (RAAS, intracellular calcium metabolism, Slow Ina and other currents, prevention of microvascular ischemia and fibrosis)

Coppini R.
Molecular targets for disease-specific treatment (RAAS, intracellular calcium metabolism, Slow Ina and other currents, prevention of microvascular ischemia and fibrosis)

14:30 - 16:00
MINICOURSE - CLINICAL SCIENCE - HOW-TO SESSION: HOW TO PERFORM AND INTERPRET

Mogensen J.
Genetic tests

Pepe G.
Assessment of extracardiac phenotype

Thiene G.
Myocardial biopsy

Mogensen J.
Clinical Case

Thiene G.
Clinical Case

ROOM-2

09:00 - 10:45
MINICOURSE - BASIC SCIENCE - MYOCARDIAL AND PERICARDIAL RESPONSES TO AUTOIMMUNE DISEASE AND INFECTION

Caforio A.
Antibody-mediated response

Pankuweit S.
Cell-mediated response

Klingel K.
Role of viral agents

11:00 - 16:30
MINICOURSE - CLINICAL SCIENCE - HOW-TO SESSION: EVALUATION OF MYOCARDIAL AND PERICARDIAL DISEASES

Rapezzi C.
A reappraisal of the ECG

Nistri S.
Hot to use Echocardiography for diagnosis and management

Aquaro G. D.
Cardiac Magnetic Resonance

P. Camici, O. Rimoldi
Nuclear Medicine and PET

Pieragnoli P.
ICD and CRT monitoring and optimization

Cappato R.
Ablation of atrial and ventricular arrhythmias in patient with cardiomyopathy

Gimeno J. R.
Illustrative case studies

ROOM-3

11:00 - 13:00
SATELLITE SYMPOSIUM INDUSTRY SPONSORED - ANDERSON-FABRY DISEASE: A NEW CHALLENGE FOR THE CARDIOLOGIST - SESSION 1- SPONSORED BY GENZYME

Elliott P.
Epidemiology of Fabry disease: which patients should be tested?

Morrone A.
Lab tests for diagnosis: the need for quality excellence

Namdar M.
ECG changes for early recognition and differentiation of Fabry disease, amyloidosis and hypertrophic cardiomyopathy

Cecchi F.
Microvascular dysfunction

14:30 - 16:30
SATELLITE SYMPOSIUM INDUSTRY SPONSORED - ANDERSON-FABRY DISEASE: A NEW CHALLENGE FOR THE CARDIOLOGIST - SESSION 2 - SPONSORED BY GENZYME

Cecchi F.
Heart disease : clinical management and outcome

Burlina A.
Neuropathic pain and stroke management

Mignani R.
Timing of ERT treatment and outcome on renal function

Weidemann F.
Optimal timing of ERT therapy: lessons from patients follow-up

27/09/2012

PLENARY-ROOM

08:50 - 10:30
SESSION 2 - GENETICS IN CLINICAL PRACTICE (IN ASSOCIATION WITH EUROPEAN SOCIETY OF HUMAN GENETICS)

Charron P.
The family as a patient: clinical, ethical, legal implications

Lopes L.
Genetic complexity in HCM revealed by high-throughput sequencing

Krishnamoorthy N.
Molecular modelling of a mutation at Hotspot of human cardiac troponin T

Girolami F.
Changing scenarios with next generation sequencing

Mogensen J.
Take home message

11:00 - 12:50
SESSION 3 - CLINICAL COURSE AND OUTCOME

Cecchi F.
Defining risk and the high risk patient with cardiomyopathy: the dilemma of ICD in primary prevention

Choudhury L.
Association of LV wall thickness and myocardial fibrosis/scar with adverse events in HCM: interaction of maximal wall thickness and late gadolinium enhancement by MRI

Biagini E.
Genetic profile of HCM patients with LV systolic dysfunction: a multicenter study

Bongiorni M. G.
Individualized choice, prevention and management of ICD - related complication

Padeletti L.
Take home message

12:50 - 14:10
LUNCHEON PANEL

Monserrat L.
Next generation genotyping: from diagnosis to prognosis

Olivotto I.
Ranolazine in chronic ischemic cardiopathy: benefits for the quality of life

14:10 - 16:00
SESSION 4 - ADVANCES IN CARDIAC IMAGING

Camici P.
Pathophysiology of coronary microvascular dysfunction in primary and secondary LVH

Masci P. G.
Interstitial myocardial fibrosis detected by cardiovascular MRI as a subclinical marker of cardiac involvement in lmna - mutation carriers

Rimoldi O.
Impact of sympathetic activity and fibrosis on microvascular function in HCM

Maron B.
Are we making good use of cardiac MRI in clinical practice?

Linhart A.
Take home message

16:30 - 18:50
SESSION 5 - LV DYSFUNCTION AND DILATED CARDIOMYOPATHY

Mestroni L.
Genotyping and clinical management of DCM

van Spaendonck-Zwarts K.
Genetic analysis in 418 index patients with idiopathic dilated cardiomyopathy: overview of 10 years' experience

Mazzanti A.
Correlations between the mutation site and phenotype in MYH7 gene

Frey N.
Role of protein degradation pathways in the pathogenesis of cardiomyopathy

Yacoub M.
Mechanisms and implications of myocardial recovery in LVAD patients

Pinto Y. M.
Take home message

28/09/2012

PLENARY-ROOM

08:40 - 10:10
SESSION 6 - HYPERTROPHIC CARDIOMYOPATHY

Ferrantini C.
Age-related decline in contractile function of ventricular myofibrils from HCM patients carrying MYBPC3 mutations

Olivotto I.
Management of HCM: the case for disease staging

Maron B.
Lessons learned from four decades of surgical myectomy, alcohol septal ablation and pacing for HOCM treatment

10:30 - 13:00
SESSION 7 - HOT TOPIC IN BASIC RESEARCH

Tardiff J.
Cardiomyopathies associated with troponin mutations: are they different?

Ferrara C.
The HCM-associated cardiac Troponin T mutation K280N accelerates tension generation and relaxation in human cardiac myofibrils

Hornung C.
Evaluation of the exon-skipping strategy in a mouse model of HCM

Sequeira V.
Perturbed length-dependent activation in human HCM with sarcomere mutations in thick and thin filament proteins

Tosi B.
Contractile function of human HCM trabeculae: INaL inhibition improves diastolic function

Van Der Velden J.
Molecular basis of diastolic heart failure

Carrier L.
Take home message

14:00 - 16:10
SESSION 8 - RESTRICTIVE CARDIOMYOPATHIES AND ARRHYTHMOGENIC VENTRICULAR CARDIOMYOPATHY

Rapezzi C.
An overview on how to improve diagnosis and prognosis of restrictive cardiomyopathies

Longhi S.
The etiology of amyloidosis influences the pathophysiology and outcome of heart failure in amyloidotic cardiomyopathy

Basso C.
ARVC diagnostic criteria made as simple as possible

Rigato I.
ARVC and pregnancy: influence and clinical course

Rasmussen T. B.
The majority of plakophilin-2 mutations in ARVC are associated with haploinsufficiency in the myocardium and epidermis

16:40 - 17:40
SESSION 9 - INFLAMMATORY MYOCARDIAL AND PERICARDIAL DISEASES

Imazio M.
Diagnosis and management of pericardial diseases

Caforio A.
Clinically suspected and definite myocarditis: the "WG consensus statement"

17:40 - 19:00
SESSION 10 - CARDIOMYOPATHIES IN CHILDREN

Limongelli G.
Step by step approach to cardiomyopathies in children

Stauffer B.
Unique myocardial molecular remodeling in children with heart failure

Cecchi F.
Final Remarks